Molecular and Cellular Basis of Visual Acuity - download pdf or read online

By P. A. Liebman (auth.), S. Robert Hilfer, Joel B. Sheffield (eds.)

ISBN-10: 1461252369

ISBN-13: 9781461252368

ISBN-10: 1461297516

ISBN-13: 9781461297512

The 7th Symposium on Ocular and visible improvement was once held in October, 1982. the purpose of the assembly used to be to strengthen a wide standpoint on visible acuity. the topic was once mentioned at the beginning when it comes to molecular occasions of photoreception, and the metabolism of the photoreceptor ele­ ments. next papers provided the improvement and complexity of the neurocircuitry and transmitter structures within the retina that technique the visible details sooner than move to the mind. The assembly concluded with a chain of papers on behavioral and physiological tools of mea­ surement of visible acuity in people, relatively children. This quantity arose from the papers provided on the assembly. We believe that the juxtaposition of analysis of greatly differing methodologies may be stim­ ulating, instead of daunting, and may generate an improved comprehend­ ing of this advanced topic. we're indebted to our colleagues: Dr. M. Mote from Temple collage, and Drs. J. Siegfried, P. Dayhaw-Barker, and L. Press from the Pennsylvania collage of Optometry for his or her services and counsel within the association of the assembly; to the audio system for his or her shows and contributions to this quantity; and to the reviewers of the manuscripts for his or her important reviews. This symposium couldn't were held with no the beneficiant help of the Temple collage university of Arts and Sciences and the Pennsyl­ vania university of Optometry. We additionally thank Merck, Sharp and Dohme, Inc. for his or her donation.

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Biochim. Biophys. Acta 665: 619-622. , R. Hoffman and M. Matthes. 1976. Photoreceptor shedding is initiated by light in the frog retina. Science 194: 1074-1076. -A. M. LaVail. 1980. Protein synthesis in retinas of rats with inherited retinal dystrophy. Exp. Eye Res. 31: 251-269. A. A. I. Posner and J. paiement. 1982. Galactose transfer to endogenous acceptors within Golgi fractions of rat liver. J. Cell BioI. 92: 139146. C. 1982. The daily light-dark cycle and rhythmic metabolism in the photoreceptor-pigment epithelium complex.

Such a strong correlation between the endogenous efferent activity and the changes in ERG amplitude provides further evidence that efferent activity mediates the circadian changes in visual sensitivity. This possibility can be directly tested by "playing back" to the eye during the day the efferent activity recorded at night. This was done by triggering a current pulse generator with a train of efferent impulses previously recorded at night from the proximal stump of the cut optic nerve. Current pulses were de- livered via a suction electrode to the distal stump of the cut optic nerve during the day.

J. Cell BioI. 42: 392-403. B. c. Chamberlain, and L. Kass The retina encodes and transmits information to the brain about the photic environment. In a number of animals the brain feeds back to the retina signals that modify the configuration of ganglion-cell receptive fields (Miles, 1970; Pearlman & Hughes, 1976), adapt the retina to changes in ambient illumination (Arechiga & Wiersma, 1969; Barlow et aI, 1977; Fleissner & Fleissner, 1978; Levinson & Burnside, 1981; Yamashita & Tateda, 1981), or control metabolic processes in the retina (Chamberlain aI, 1980).

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Molecular and Cellular Basis of Visual Acuity by P. A. Liebman (auth.), S. Robert Hilfer, Joel B. Sheffield (eds.)

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